挤压
材料科学
硅酮
成像体模
柱塞
复合材料
生物医学工程
多孔性
电介质
硅油
空隙(复合材料)
松弛法
磁共振成像
光学
放射科
光电子学
物理
自旋回波
医学
作者
Conor Cristant,Kamal Kolasangiani,Siddharth Sadanand,Habiba Bougherara,Dafna Sussman
出处
期刊:Polymers
[Multidisciplinary Digital Publishing Institute]
日期:2023-12-11
卷期号:15 (24): 4670-4670
标识
DOI:10.3390/polym15244670
摘要
Phantoms with tissue-mimicking properties play a crucial role in the calibration of medical imaging modalities, including Magnetic Resonance Imaging (MRI). Among these phantoms, silicone-based ones are widely used due to their long-term stability in MR imaging. Most of these phantoms are manufactured using traditional pour-mold techniques which often result in the production of air bubbles that can damage the phantom. This research investigates the feasibility of utilizing extrusion techniques to fabricate silicone phantoms and explores the effects of extrusion parameters including plunger speed and nozzle diameter on void content, T1 and T2 relaxation times, and dielectric properties. A custom double-syringe silicone extrusion apparatus was developed to prepare the silicone samples. The void content, relaxometry, and dielectric properties of extruded samples were measured and compared with traditional poured samples. The results show that extrusion parameters can affect the void content of the silicone samples. The presence of voids in the samples resulted in lower T1 values, indicating an inverse relationship between void content and relaxometry. This study demonstrates the potential of extrusion techniques for manufacturing silicone phantoms with reduced air bubble formation and provides valuable insights into the relationship between extrusion parameters and phantom properties.
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