烯丙基重排
化学
立体选择性
二茂铁
部分
膦酸盐
叠氮化物
胺气处理
烯烃纤维
叠氮化钠
有机化学
组合化学
药物化学
催化作用
电化学
电极
物理化学
作者
Lingling Guo,Wanrong Zhao,Yan-Peng Gao,Manman Wu,Shufeng Chen
标识
DOI:10.1021/acs.joc.3c02686
摘要
A general and practical methodology for the regio- and stereoselective synthesis of multifunctional tetrasubstituted allylic amines and azides based on iodoamination of ferrocene-containing allenylphosphonates with anilines and sodium azide is described. A tetrasubstituted olefin moiety, as well as an iodine atom, a phosphonate, and a ferrocene group, are installed to the allylic amine motif simultaneously in moderate to good yields.
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