前药
喜树碱
化学
共轭体系
药理学
唾液酸
化疗
癌症研究
癌症化疗
生物化学
生物
医学
有机化学
内科学
聚合物
作者
Huiling Dong,Xuefei Huang,Xuanjun Wu
摘要
A novel CPT prodrug (CPT-ss-Sia) has been developed by the conjugation of 9-thiol-sialic acid (9-SH-Sia) with camptothecin (CPT). Intravenous administration of CPT-ss-Sia significantly inhibited the growth of multiple types of tumors.
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