Objective To investigate 8 deaths caused by iatrogenic bile duct injury.Methods Clinical data of the 8 deaths caused by iatrogenic bile duct injury were analyzed retrospectively.Results Among all the deaths,6 were due to severe infection after open cholecystectomy(OC)and 2 after laparoscopic cholecystectomy(LC).All the deaths showed bile duct injury.Conclusions Iatrogenic bile duct injury is a severe complication.During cholecystectomy doctors should prevent bile duct injury.Once bile duct is impaired,they should respond as quick as possible and take active measures to avoid death occurence.