Histamine: Biology and Medical Aspects

Preface: Histamine, the Oldest Biogenic Amine, Revisited in the New Millennium: Watanabe, T. Introduction: Falus, A. 1. Histamine Biology Histamine: Fundamentals of Biological Chemistry: Noszal, B. Kraszni, M. Racz, A. 2. Enzymes in Histamine Metabolism Histidine Decarboxylase (HDC) Enzyme and Gene: Darvas, Z. Falus, A. Diamine Oxidase (DAD) Enzyme and Gene: Schwelberger, H.G. Histamine N-Methyltransferase (HNMT) Enzyme and Gene: Schwelberger, H.G. 3. Histamine Receptors Histamine Receptors: H1, H2, H3, H4, and the Putative 'Hic' (Intracellular) Receptor. Coding Genes and Gene Products, 'in silico' and Experimental Data: Igaz, P. Hargita, H. Histamine Agonists, Antagonists, and Inverse Agonists: Tomoskozi, Z. Signal-Transduction Pathways of Histamine Receptors: Lazar-Molnar, E. 4. Histamine in the Immune System Characterization of Histamine Release by Mast Cells, Basophils, and Monocytes: Watt, A.P. Ennis, M. Cytokines, Chemokines, and Histamine: Igaz, P. Falus, A. Complement Activation and Histamine Release: Erdei, A. Andrasfaivy, M. The Role of Histamine in the Hepatic Acute Phase Reaction and Systemic Inflammation: Fillop, A.K. Histamine and Sepsis: Matauds, N. Hattorl, Y. Gando, S. Histamine in Allergy: Herjavecz, I. Hirschberg, A. 5. Histamine in the Gastrointestinal System Histamine and Gastric Ulcer. Secretory and Inflamatory Histamine in the Stomach: Hunyady, B. Histamine in Food: Sarkadi, L. Histamine Neurons Activated by Mastication Satiate Appetite and Upregulate Their Energy Expenditure: Sakata, T. 6. Histamine in Cell Proliferation and Differentiation Histamine and Cell Proliferation: Pos, Z. Hegyesi, H. Rivera, E.S. Histamine and Polyamines: Laszio, V. Histamine and Hematopoiesis: Schneider, E. Dy, M. Histamine in Embryonic Development: Karlstedt, K. Panula, P. 7. Histamine in the Nervous System Histamine as a Neurotransmitter in the Central Nervous System: Yanal, K. Watanabe, T. Histamine and the Blood-Brain Barrier: Deli, M.A. Abraham, C.S. Histamine in CNR-Resident Non-Neural Cells: Huszti, Z. Histamine in Neuroendocrine Regulation: Kovacs, K.J. The Influence of Histamine on Memory: Passani, M.B. Cangioli, I. Blandina, P. 8. Other Medical Aspects of Histamine Histamine and the Cardiovascular System: Jochem, J. Zwirska-Korczals, K.W. Connection between Histamine and the Sexual Steroids: Pap, E. Histamine and Surgery: Celik, I. Lorenz, W. 9. Conclusion Lessons from the HDC-KO Mice Newly Recognized Aspects of Histamine Biology: Watanabe, T. Falus, A. Subject Index