亲爱的研友该休息了!由于当前在线用户较少,发布求助请尽量完整的填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!身体可是革命的本钱,早点休息,好梦!

The Problem of Appetite Loss After Major Abdominal Surgery

医学 食欲 减肥 普通外科 梅德林 腹部外科 重症监护医学 外科
作者
Martin Wagner,Pascal Probst,Michael Haselbeck-Koebler,Johanna M Brandenburg,Eva Kalkum,Dominic Störzinger,Jens Kessler,Joe J Simon,Hans-Christoph Friederich,Michaela Angelescu,Adrian T Billeter,Thilo Hackert,Beat P Müller-Stich,Markus W Büchler
出处
期刊:Annals of Surgery [Ovid Technologies (Wolters Kluwer)]
卷期号:Publish Ahead of Print
标识
DOI:10.1097/sla.0000000000005379
摘要

To systematically review the problem of appetite loss after major abdominal surgery.Appetite loss is a common problem after major abdominal surgery. Understanding of etiology and treatment options is limited.We searched Medline, Cochrane Central Register of Controlled Trials, and Web of Science for studies describing postoperative appetite loss. Data were extracted to clarify definition, etiology, measurement, surgical influence, pharmacological, and nonpharmacological treatment. PROSPERO registration ID: CRD42021224489.Out of 6144 articles, we included 165 studies, 121 of which were also analyzed quantitatively. A total of 19.8% were randomized, controlled trials (n = 24) and 80.2% were nonrandomized studies (n = 97). The studies included 20,506 patients undergoing the following surgeries: esophageal (n = 33 studies), gastric (n = 48), small bowel (n = 6), colon (n = 27), rectal (n = 20), hepatobiliary (n = 6), and pancreatic (n = 13). Appetite was mostly measured with the Quality of Life Questionnaire of the European Organization for Research and Treatment of Cancer (EORTC QLQ C30, n = 54). In a meta-analysis of 4 randomized controlled trials gum chewing reduced time to first hunger by 21.2 hours among patients who had bowel surgery. Other reported treatment options with positive effects on appetite but lower levels of evidence include, among others, intravenous ghrelin administration, the oral Japanese herbal medicine Rikkunshito, oral mosapride citrate, multidisciplinary-counseling, and watching cooking shows. No studies investigated the effect of well-known appetite stimulants such as cannabinoids, steroids, or megestrol acetate on surgical patients.Appetite loss after major abdominal surgery is common and associated with increased morbidity and reduced quality of life. Recent studies demonstrate the influence of reduced gastric volume and ghrelin secretion, and increased satiety hormone secretion. There are various treatment options available including level IA evidence for postoperative gum chewing. In the future, surgical trials should include the assessment of appetite loss as a relevant outcome measure.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
行者无疆完成签到,获得积分10
33秒前
Suchen完成签到 ,获得积分10
1分钟前
2分钟前
SimpleKwee发布了新的文献求助10
2分钟前
2分钟前
MXNCVDN完成签到 ,获得积分10
4分钟前
4分钟前
zhangfan完成签到,获得积分20
4分钟前
5分钟前
zuhangzhao发布了新的文献求助10
5分钟前
迅速的蜡烛完成签到 ,获得积分10
5分钟前
xmhxpz完成签到,获得积分10
6分钟前
俏皮的安萱完成签到 ,获得积分10
6分钟前
小白完成签到 ,获得积分10
7分钟前
阿巴完成签到 ,获得积分10
7分钟前
8分钟前
SimpleKwee发布了新的文献求助10
9分钟前
SimpleKwee完成签到,获得积分10
9分钟前
Lucas应助庾稀采纳,获得10
11分钟前
lunar完成签到 ,获得积分10
13分钟前
苯酚完成签到 ,获得积分10
14分钟前
zshjwk18完成签到,获得积分10
15分钟前
17分钟前
庾稀发布了新的文献求助10
17分钟前
黄花菜完成签到 ,获得积分10
17分钟前
fev123完成签到,获得积分10
18分钟前
JAJ完成签到 ,获得积分10
20分钟前
清秀的怀蕊完成签到 ,获得积分10
20分钟前
OCDer发布了新的文献求助500
21分钟前
今后应助科研通管家采纳,获得10
22分钟前
寻找土豆的灯完成签到 ,获得积分10
22分钟前
英姑应助科研通管家采纳,获得10
24分钟前
Larock完成签到 ,获得积分10
24分钟前
欣喜雪晴完成签到 ,获得积分10
26分钟前
席康完成签到 ,获得积分10
27分钟前
nianshu完成签到 ,获得积分10
28分钟前
Spring完成签到,获得积分10
32分钟前
传奇3应助guan采纳,获得10
32分钟前
33分钟前
缪静柏发布了新的文献求助10
33分钟前
高分求助中
Un calendrier babylonien des travaux, des signes et des mois: Séries iqqur îpuš 1036
Sustainable Land Management: Strategies to Cope with the Marginalisation of Agriculture 1000
Corrosion and Oxygen Control 600
Python Programming for Linguistics and Digital Humanities: Applications for Text-Focused Fields 500
Heterocyclic Stilbene and Bibenzyl Derivatives in Liverworts: Distribution, Structures, Total Synthesis and Biological Activity 500
重庆市新能源汽车产业大数据招商指南(两链两图两池两库两平台两清单两报告) 400
Division and square root. Digit-recurrence algorithms and implementations 400
热门求助领域 (近24小时)
化学 材料科学 医学 生物 有机化学 工程类 生物化学 纳米技术 物理 内科学 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 电极 光电子学 量子力学
热门帖子
关注 科研通微信公众号,转发送积分 2545741
求助须知:如何正确求助?哪些是违规求助? 2175669
关于积分的说明 5600211
捐赠科研通 1896371
什么是DOI,文献DOI怎么找? 946268
版权声明 565379
科研通“疑难数据库(出版商)”最低求助积分说明 503557