Wheat-related disorders : making sense of Coeliac Disease and other reactions to wheat and gluten : review article

Globally, wheat-free and gluten-free products and diets have become fashionable, indicating a first glance at the prevalence of gluten-related disorders is very high. Clinicians will therefore regularly be confronted with patients who suspect that they react to wheat or gluten. Most patients attribute any adverse reaction to wheat or gluten to an allergy. The greatest challenge to the clinician is to distinguish between the different gluten-related disorders like Coeliac Disease, wheat allergy,wheat intolerance and other gut complaints like irritable bowel syndrome (IBS).