T细胞
抗原
抗体
嵌合抗原受体
T细胞受体
免疫学
免疫疗法
癌症研究
细胞毒性T细胞
癌症
生物
医学
免疫系统
体外
内科学
生物化学
作者
Suman Paul,Alexander H. Pearlman,Jacqueline Douglass,Brian J. Mog,Emily Han-Chung Hsiue,Michael S. Hwang,Sarah R. DiNapoli,Maximilian F. Konig,Patrick A. Brown,Katharine M. Wright,Surojit Sur,Sandra B. Gabelli,Yana Li,Gabriel Ghiaur,Drew M. Pardoll,Nickolas Papadopoulos,Chetan Bettegowda,Kenneth W. Kinzler,Shibin Zhou,Bert Vogelstein
标识
DOI:10.1126/scitranslmed.abd3595
摘要
Bispecific antibodies directed against T cell receptor β chains promote killing of human T cell cancers while preserving most healthy T cells.
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