Rhodium(I)-Catalyzed Dearomative Cycloisomerization of 1H-Indole N-Tethered o-Alkynylphenyl Nitrones and Application to Spirocyclic Pyrido[1,2-a]indole Synthesis

A synthetic method for the synthesis of indoline-fused polycyclic tropane scaffolds that relies on the rhodium(I)-catalyzed highly regio- and diastereoselective 6-exo-dig cyclization/internal redox(IR)/azomethine ylide formation/dearomative [3 + 2] cycloaddition of...