交联羧甲基纤维素钠
佐匹克隆
立即释放
压缩(物理)
数学
医学
色谱法
药理学
材料科学
化学
剂型
失眠症
复合材料
硬脂酸镁
作者
Lakshmi Devi Gottemukkula,Rishika Singh,N.D. Prathyusha,J. Shetty Akhila,B. Devender,Ramya Sri S
出处
期刊:Research journal of pharmacy and technology
[Diva Enterprises Private Limited]
日期:2023-08-31
卷期号:: 3755-3758
标识
DOI:10.52711/0974-360x.2023.00620
摘要
The current study's objective is to directly compress a Zopiclone rapid release tablet and assess it. The superdisintegrants (crospovidone, croscarmellose sodium, fenugreek) were used to hasten drug release from tablets. The prepared tablets pre-compression, post-compression characteristics were scrutinised. The interactions between the medication excipients were investigated using FTIR. The research shows that direct compression F3 formulations had a faster drug release of 100.05% over a 45-minute period than other Zopiclone formulations, which had lower dissolving rates when utilising Crospovidone.
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