Dynamic Resting-State Functional Connectivity in Migraineurs

Functional magnetic resonance imaging (fMRI) is widely used to detect changes in the resting-state brain networks of migraine patients. Functional connectivity fMRI analysis examines the functional organization of the brain based on temporal correlations of blood oxygen level-dependent signal changes in different brain regions. Most previous resting-state fMRI studies have assumed that functional connectivity between brain regions remains relatively stable over time. However, it is now known that the brain is a complex system that undergoes time-dependent dynamics. Therefore, functional connectivity may change over time. In recent years, resting-state fMRI analysis has evolved from the detection of static coupling to the study of dynamic connectivity. However, studies of dynamic functional connectivity in migraine patients are limited. Related studies have shown that dynamic functional connectivity analysis reveals significant changes in connectivity and abnormal networks not found in static functional connectivity analysis.