Banff Human Organ Transplant Transcripts Correlate with Renal Allograft Pathology and Outcome: Importance of Capillaritis and Subpathologic Rejection
肾移植
病理
移植
医学
内科学
作者
Ivy A. Rosales,Grace K. Mahowald,Kristen Tomaszewski,Kiyohiko Hotta,Naoya Iwahara,Takuya Otsuka,Takahiro Tsuji,Yusuke Takada,Ellen Acheampong,Milagros Araujo-Medina,Amy Bruce,Andrea Rios,Anthony B. Cosimi,Nahel Elias,Tatsuo Kawai,Hannah Gilligan,Kassem Safa,Leonardo V. Riella,Nina Tolkoff-Rubin,Winfred W. Williams
Peritubular capillary inflammation and DSA are the primary drivers of AMR transcript elevation. Transcripts revealed subpathological evidence of AMR, which often preceded histologic CAMR and subpathological evidence of TCMR that predicted graft loss in CAMR.