Visible-Light-Mediated Radical α-C(sp3)─H gem-Difluoroallylation of Amides with Trifluoromethyl Alkenes via Halogen Atom Transfer and 1,5-Hydrogen Atom Transfer

-difluoroalkene motifs as carbonyl bioisosteres incorporated concisely to some complex molecules, including gemfibrozil and estrone derivatives, presenting great potential for late-stage functionalization of drugs, natural products, and bioactive intermediates. Mechanistic investigations suggest a radical pathway combining XAT and 1,5-HAT.