The Deposition of C_1q on Type V Lupus Nephritis and Primary Membranous Nephropathy Significance of Differential Diagnosis

Objective:To find out the difference and significance of the deposition of C1q in pure class V lupus nephritis,primary membranous nephropathy and atypical membranous nephropathy.Methods:C1q immunohistochemical staining for the pure class V lupus nephritis,membranous nephropathy and atypical membranous nephropathy was performed,and collected the clinical and Serological characteristics for the statistical analysis.Results:C1q deposited in the kidney of pure class V lupus nephritis,and not in the primary membranous nephropathy.Some patients with atypical membranous nephropathy could found out the deposition of C1q,the positive rate was approximated with pure class V lupus nephritis,and had significant difference with membranous nephropathy.Conclusion:Some patients with atypical membranous nephropathy and the deposition of C1q may be early pure class V lupus nephritis.