Objective To evaluate the application of multi-slice spiral CT and MRA in the diagnosis of aortic dissection.Methods 189 patients of aortic dissection were confirmed by surgery or angiography,the coincidence rate of diagnosis were observed using multi-slice spiral CT angiography(MSCTA),magnetic resonance angiography(MRA)and transthoracic echocardiography(TTE).Results 68 cases of Debakey I type,22 cases of Debakey Ⅱ type,99 cases of Debakey IlI type were confirmed by multi-slice spiral CT angiography(MCTA),magnetic resonance angiography(MRA)and transthoracic echocardiography(TTE),in which multi-slice spiral CT angiography(MSCTA)and magnetic resonance angiography(MRA)diagnosis of aortic dissection and confirmed by surgery or angiography were more in line with rate of 100%.Conclusion Aortic dissection can be confirmed by multi-slice spiral CT or magnetic resonance angiography.Compered with magnetic resonance angiography,multi-slice spiral CT angiography has the short scanning time,and it can reduce the risk of patients with hemodynamic instability.Multi-slice spiral CT angiography in aortic dissection is a safe,rapid,noninvasive and effective diagnostic method.