Study on Homeobox Gene

There was a highly conservative homeobox in nearly all homeobox gene family,which used for encoding transcription regulatory factors(homeobox protein) and generated the accurate regulating action in cells proliferation and differentiation.The mutation of homeobox gene not only resulted in development malformation,but also had a close relationship with the occurrence and development of some tumours.The structural features of homeobox gene and the effect in tumours were summarized.