生物
神经科学
诱导多能干细胞
小头畸形
类有机物
人脑
神经系统
大脑发育
神经干细胞
哺乳动物大脑
计算生物学
干细胞
细胞生物学
遗传学
基因
胚胎干细胞
作者
Stuart M. Chambers,Jason Tchieu,Lorenz Studer
出处
期刊：Cell Stem Cell
[Elsevier BV]
日期：2013-10-01
卷期号：13 (4): 377-378
被引量：22
标识
DOI：10.1016/j.stem.2013.09.010
摘要
A major barrier in understanding nervous system development is modeling the cellular interactions that form the human brain. Recently, in the journal Nature, Lancaster et al. (2013) established a protocol for culturing pluripotent stem cell (PSC)-derived "cerebral organoids" that mimics the developing human brain's cellular organization, segregates into distinct brain regions, and models microcephaly.
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