固定化酶
纳米技术
纳米颗粒
纳米材料
化学
生化工程
组合化学
酶
材料科学
生物化学
工程类
作者
Fatemeh Borzouee,Jaleh Varshosaz,Reza Ahangari Cohan,Dariush Norouzian,Razieh Taghizadeh Pirposhteh
标识
DOI:10.2174/0929867328999201214225249
摘要
Abstract:: Immobilization techniques have been popularly used to preserve the operational stability of the enzymes for industrial applications. The three main components of an immobilized enzyme system are the enzyme, the matrix/support, and the technique of immobilization. So far different supports have been developed to improve the efficiency of the immobilized enzymes. But in the recent decade, nanotechnology has been considerable research interest in the field of immobilized enzyme carriers. The materials at the nano-scale due to their unique physicochemical properties including; specific surface area, mass transfer limitation, and effective enzyme loading, are considered as interesting matrices for enzyme immobilization. This review describes techniques employed to immobilize enzymes and provides an integrated focus on the most common nanoparticles for enzyme conjugation. Additionally, the pros and cons of nanoparticles as immobilization matrices are also discussed. Depending on the type of enzyme and its application, in this review, the researchers are directed to select an appropriate method and support for enzyme immobilization in terms of enzyme stability and functionality.
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