Study on fermentation kinetics of γ-polyglutamic acid production by Bacillus subtilis

The fermentation kinetics of γ-polyglutamic acid production by Bacillus subtilis was investigated in this study. A series kinetic model for microorganism growth,γ-polyglutamic acid formation and substrate consumption during fermentation were constructed based on the Logistic equa-tion. The data was analyzed with the MATLAB software to generate the kinetics parameters of γ-polyglutamic acid production with batch fermenta-tion. The experimental data and models were compared. The results showed the model could fit the experimental data well,and the model appeared to provide a reasonable description for the batch fermentation process.