In recent years,researchers have paid close attention to the role of synaptic plasticity in learning and memory.Synaptic is a key part of neural information transmission,and synaptic plasticity is considered as synaptic changes,the new synaptic formation and the establishment of transmission performance.Synaptic plasticity is the molecular basis of learning and memory,which mediates the transmission of nerve excitability,and has a major influence on synaptic plasticity of neurons establishment,therefore is closely related to learning and memory.Here is to make a review on the molecular mechanisms of synaptic plasticity in learning and memory.