The effects of two antibiotics,Chloromycetin and Nicotinic Norfloxacinum,on population growth of rotifer(Brachionus plicatilis) were studied by means of population accumulation culture.The population growth of rotifer was significantly(P0.01) affected when exposed to different doses of Chloromycetin,of which a concentration of 0.012 5 mg/mL could promote rotifer population to grow.When concentration increases between 0.025 0—0.050 0 mg/mL,however,the growth was inhibited,and the inhibition is significant at the concentration of 0.050 0 mg/mL.The dosage of Nicotinic Norfloxacinum affects rotifers' population growth significantly(P0.01),low dosage(0.25 and 0.50 mg/mL) promotes growth and high dosage(0.75 and 1.00 mg/mL) inhibits it.