受体
血清素
萧条(经济学)
神经科学
心理学
5-羟色胺受体
重性抑郁障碍
精神科
医学
认知
内科学
经济
宏观经济学
作者
Еlena V. Mitroshina,Ekaterina A. Marasanova,Maria V. Vedunova
标识
DOI:10.3390/ijms242216416
摘要
Understanding the neurobiological underpinnings of depressive disorder constitutes a pressing challenge in the fields of psychiatry and neurobiology. Depression represents one of the most prevalent forms of mental and behavioral disorders globally. Alterations in dimerization capacity can influence the functional characteristics of serotonin receptors and may constitute a contributing factor to the onset of depressive disorders. The objective of this review is to consolidate the current understanding of interactions within the 5-HT receptor family and between 5-HT receptors and members of other receptor families. Furthermore, it aims to elucidate the role of such complexes in depressive disorders and delineate the mechanisms through which antidepressants exert their effects.
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