Conventional optical coherence tomography (OCT) has dramatically changed clinical practice over the last 15 years and is now an indispensable tool for clinicians in the detection and management of most ocular diseases. The rapid rise and integration of OCT technology into clinics around the world is principally due to the high-resolution crosssectional images and thickness maps that provide critical structural information of the retina and choroid that cannot otherwise be visualized or appreciated. A new major advancement in OCT technology now enables the same OCT devices to image the retinal and choroidal microvasculature with extremely fine detail. Previously, this could be performed only with fluorescein angiography (FA) or indocyanine green angiography; however, now OCT devices can image the same vasculature without dyes or injections, using the same noninvasive scanning methods as in conventional OCT. In fact, the microvasculature imaged by optical coherence tomography angiography (OCTA) may reveal even finer detail than FA as well as allow visualization over specific depth-resolved tissue layers. It is likely that OCTA will gain a prominent role in clinical imaging and may even become an important everyday tool similar to conventional OCT.