金黄色葡萄球菌
微生物学
化学
细菌
生物
遗传学
作者
Feng Yang,Weize Sun,Xue‐Song Wang,Qianxiong Zhou
标识
DOI:10.1002/chem.201903923
摘要
Ruthenium(II) polypyridyl complexes featuring peripheral quaternary ammonium structures were found to be able to selectively inactivate Gram-positive Staphylococcus aureus (S. aureus), including methicillin-resistant S. aureus (MRSA) upon visible light irradiation, but have low phototoxicity toward 293T cells, L02 cells and lack hemolysis toward rabbit red blood cells (RBC), exhibiting promising potential as a novel type of antimicrobial photodynamic therapy (aPDT) agents.
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