QUALITATIVE ANALYSIS OF CARICA PAPAYA LEAVES TABLET FORMULATION AND STUDY OF FRAGMENTATION PATTERN OF RUTIN

The chemical constitution of Carica papaya leaves tablets and the fragmentation pattern of rutin is poorly investigated. Rutin was found to a constituent of tablet formulation. This work reports a study on the fragmentation pattern of rutin by electrospray ionization with multistage mass spectrometry in positive mode. Potential dissociation pathway for rutin is proposed. The fragmentation pattern provides important information for its determination by liquid chromatography coupled to mass spectrometry.