Recent Advances and the Prospect of Hypervalent Iodine Chemistry

Abstract Nowadays, hypervalent iodine chemistry has remarkably advanced in parallel with the emergence of novel hypervalent iodine reagents. Hypervalent iodine reagents, due to their outstanding characteristics including rich reactivities, excellent chemoselectivity, stability, and environmental friendliness, are becoming more and more popular in the synthetic organic chemistry. In this Account, a number of recent elegant research works and our perspective on the future of hypervalent iodine chemistry is presented. 1 Introduction 2 Recent Advances and Discussion 2.1 Novel Reactivities of Hypervalent Iodine Reagents 2.2 Atom-Economical Reactions Promoted by Hypervalent Iodine Reagents 2.3 Other Applications of Hypervalent Iodine Reagents 2.4 The Applications of DFT Calculations in Elucidating Reaction Mechanism Involving Hypervalent Iodine Reagents 3 Outlook and Conclusion