Palladium‐Catalyzed CC Bond Formation To Construct 1,4‐Diketones under Mild Conditions

Palladium can do it! A novel palladium-catalyzed reaction between the bulky α-carbon centers of two ketones has led to the construction of 2,3-diaryl-1,4-diketones by employing α-chloroketones as electrophiles and zinc ketone enolates as nucleophiles (see scheme). This reaction allows the synthesis of bulky 1,4-diketones and is complementary with classic nucleophilic substitution reactions. Detailed facts of importance to specialist readers are published as "Supporting Information". Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.