化学
布朗斯特德-洛瑞酸碱理论
催化作用
对映选择合成
组合化学
光催化
硅烷化
广谱
组分(热力学)
有机化学
光催化
热力学
物理
作者
Jie Wei,Yurong Tang,Qian Yang,Hongxiang Li,Dongxian He,Yunfei Cai
出处
期刊:Organic Letters
[American Chemical Society]
日期:2022-10-21
卷期号:24 (43): 7928-7933
被引量:1
标识
DOI:10.1021/acs.orglett.2c03040
摘要
An enantioselective three-component rearrangement of alkenylfurans with various cycloalkyl silyl peroxides and anilines has been developed by merging photoredox catalysis with chiral Brønsted acid catalysis. This protocol provides expedient access to a broad spectrum of ketoalkyl-functionalized 4-aminocyclopentenones in high yields with excellent enantio- and diastereoselectivities. Diverse functional groups can be introduced via facile product derivations.
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