Genome‐Wide Blood DNA Methylation Profiling in Birch Pollen Allergic Patients Undergoing Allergen‐Specific Immunotherapy

GCNT2 and ABRA are implicated in Rho-signaling, a pathway involved in Th2 differentiation. GCNT2 modulates the SMAD-dependent TGF-β pathway, indicating a role in mediating AIT-induced immunotolerance. This is the first longitudinal study investigating DNA methylation changes induced by birch pollen AIT.