A europium(III) metal-organic framework as effective fluorescence sensor for detection of ofloxacin antibiotic

Antibiotic overuse, a critical global concern, poses significant threats to both the eco-environment and human health. Thus, selective and sensitive detection of antibiotics is an extremely important issue. Herein, a europium(III) metal-organic framework Eu2(FA)3(H2O)4·2DMAC (1) (FA = fumaric acid, DMAC = dimethylacetamide) was synthesized by solvothermal strategy. Single-crystal structural analyses indicate that Eu3+ ions are double-bridged by carboxylate groups of fumarate ligands to create one-dimensional (1D) infinite chains, which further form a 3D pillared-layer framework. 1 exhibits superior fluorescence detection performance toward ofloxacin (OFLX) with a high quenching efficiency Ksv of 4.1 × 104 M−1 and low detection limit of 2.4 × 10−6 M, and demonstrates excellent anti-interference properties and durability. Furthermore, the mechanism of fluorescence quenching was mainly attributed to static quenching process and internal filtration effect.