阻塞性睡眠呼吸暂停
肥胖
体质指数
医学
呼吸暂停
睡眠呼吸暂停
持续气道正压
随机对照试验
血压
安慰剂
置信区间
多导睡眠图
麻醉
内科学
病理
替代医学
作者
Atul Malhotra,Ronald R. Grunstein,Ingo Fietze,Terri E Weaver,Susan Redline,Ali Azarbarzin,Scott A. Sands,Richard J Schwab,Julia P. Dunn,Sujatro Chakladar,Mathijs C. Bunck,Josef Bednařík
标识
DOI:10.1056/nejmoa2404881
摘要
Among persons with moderate-to-severe obstructive sleep apnea and obesity, tirzepatide reduced the AHI, body weight, hypoxic burden, hsCRP concentration, and systolic blood pressure and improved sleep-related patient-reported outcomes. (Funded by Eli Lilly; SURMOUNT-OSA ClinicalTrials.gov number, NCT05412004.).
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