组织发生
生物
上皮
苗勒管
缪勒模仿
胚胎学
女性生殖道
子宫内膜
卵巢
子宫内膜
解剖
病理
医学
子宫
动物
内分泌学
癌症
免疫学
子宫颈
免疫组织化学
遗传学
作者
Theresa Austria,Louis Dubeau
出处
期刊:Cold Spring Harbor Perspectives in Medicine
[Cold Spring Harbor Laboratory]
日期:2023-04-25
卷期号:13 (7): a040642-a040642
被引量:1
标识
DOI:10.1101/cshperspect.a040642
摘要
The embryology of the female reproductive organs is reviewed focusing on aspects relevant to the histogenesis of reproductive neoplasms. The evidence reviewed suggests that (1) there is no embryological link between the ovarian surface epithelium and the coelomic epithelium; (2) the ovarian surface epithelium is not composed of pluripotent cells that readily differentiate into various components of the reproductive tract before or after birth; (3) there is no embryological link between the ovarian surface epithelium and the Müllerian ducts, from which internal female reproductive organs other than the ovaries, including the endocervix, endometrium, and fallopian tubes, are derived; and (4) there is an embryological link between the Müllerian ducts and the renal collecting system, perhaps accounting for clear cell differentiation in some gynecological malignancies. Implications for our understanding of the origin of the tumors historically classified as ovarian epithelial neoplasms are discussed.
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