An iridium(iii)-based photosensitizer disrupting the mitochondrial respiratory chain induces ferritinophagy-mediated immunogenic cell death

A mitochondria-localizing iridium( iii ) photosensitizer produces singlet oxygen and superoxide anion radicals upon two-photon irradiation, disrupting the mitochondrial respiratory chain and inducing ferritinophagy and immunogenic cell death.