重氮乙酸乙酯
区域选择性
可见光谱
卡宾
化学
光催化
催化作用
组合化学
光化学
有机化学
环丙烷化
材料科学
光电子学
作者
Suvam Bhattacharjee,Sudip Laru,Sadhanendu Samanta,Mukta Singsardar,Alakananda Hajra
出处
期刊:RSC Advances
[The Royal Society of Chemistry]
日期:2020-01-01
卷期号:10 (47): 27984-27988
被引量:19
摘要
A visible light-mediated regioselective C3-ethoxycarbonylmethylation of imidazopyridines with ethyl diazoacetate (EDA) was achieved under mild reaction conditions. In contrast to the carbene precursors from α-diazoester a first C3-ethoxycarbonylmethylation of imidazopyridines via a radical intermediate has been established. The present methodology provides a concise route to access pharmacologically useful esters with wide functional group tolerance in high yields.
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