Airway management with cuffed endotracheal intubation for General Anaesthesia(GA) is an integral part of an anesthesiologist's, Tracheal intubation results in stretch stimuli in the trachea caused by the tube and its cuff may cause ischemia of the mucosal vessels followed by serious complications such as ciliary loss, inflammation,ulceration, bleeding and tracheal stenosis. Coughing during emergence from General Anaesthesia can result in hypertension, tachycardia, increased intraocular and intracranial pressures, myocardial ischemia, broncho spasm and surgical bleeding. Post-operative sore throat is a common complaint in patients receiving general anesthesia following endotracheal intubation, with incidence ranging from 21–65%. which can be accompanied by cough, laryngitis, tracheitis, dysphagia or hoarsenes. Though considered as a minor complication, it may cause significant post-operative morbidity and patient dissatisfaction. This study tries to understand the better drug.