生态毒性
恩诺沙星
生物降解
环境化学
污染物
沉积物
生物群
环境科学
抗生素
生物
化学
生态学
微生物学
毒性
环丙沙星
有机化学
古生物学
作者
Tanare C. R. Ferreira,Maranda Esterhuizen-Londt,Marcelo Zaiat,Stephan Pflugmacher
标识
DOI:10.1080/15320383.2018.1478798
摘要
Various pharmaceutical drugs are being detected in different environmental compartments such as surface waters, groundwater, and sediment; a major concern since they are biologically active substances which can interfere with biological systems affecting the native biota. Among these drugs, antimicrobials are especially worrisome mainly due to the development of bacterial resistance. The aims of this study were to investigate if enrofloxacin, an emergent antibiotic pollutant, could be biodegraded in lake sediment, identify its break down products and to determine if these products have antimicrobial properties or are toxic. Three biodegradation products were identified and the antibiotic susceptibility assay proved that the products formed did not display antibiotic effects. Ecotoxicity testing with green algae suggested that the degradation products do not cause adverse effects statistically. However, it is suggested that further investigations are needed to identify the mechanism of degradation and the microbes involved.
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