果胶
化学
抗菌剂
核化学
傅里叶变换红外光谱
三吡啶
抗菌活性
多糖
食品化学
有机化学
金属
细菌
组合化学
食品科学
超分子化学
绿色化学
化学工程
生物
工程类
遗传学
晶体结构
作者
Enas A. Hassan,Wafaa S. Abou Elseoud,Mahmoud T Abo-Elfadl,Mohamed Hassan
标识
DOI:10.1016/j.carbpol.2021.118230
摘要
Pectin is widely used in food and pharmaceutical industries. However, due to its polysaccharide nature it lacks antimicrobial activity. In the current work, new pectin derivatives with interesting optical and antimicrobial properties were prepared via supramolecular chemistry utilizing Fe- or Cu-terpyridine (Tpy-Fe and Tpy-Cu) motifs. To proof derivatization of pectin, ultraviolet-visible spectroscopy (UV-Vis) and Fourier Transform infrared (FTIR) were used. In addition, the prepared pectin derivatives retained the known emulsification activity of the non-modified sugar beet pectin as seen from the particle size analysis of oil-in-water emulsions. The prepared derivatives showed antibacterial activity toward selected Gram-positive and Gram-negative bacteria. In addition, cytotoxicity test showed that the Tpy-Fe-pectin derivative was non-toxic to cells of human hepatocarcinoma, breast adenocarcinoma MCF7, and colorectal carcinoma cells at concentrations up to 100 μg/ml, while Tpy-Cu-pectin had moderate toxicity toward the aforementioned cells at the same concentration levels. The prepared derivatives could have potential applications in emulsions with antibacterial activity.
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