Medulloblastoma: From Origin to Treatment

Medulloblastoma is the most frequent childhood brain tumor. Medulloblastoma affects the cerebellum, the brain region that regulates motor coordination and is also involved in certain cognitive functions. Medulloblastoma is a heterogeneous tumor, and recent advances in high-throughput genomic techniques have allowed medulloblastoma to be classified into four molecularly distinct subgroups: the SHH-group, WNT-group, group 3, and group 4 medulloblastoma.