纳米技术
癌症免疫疗法
体内分布
免疫疗法
纳米医学
肿瘤微环境
癌症
癌症治疗
材料科学
医学
纳米颗粒
生物
生物技术
内科学
体内
作者
Faisal Raza,Hajra Zafar,Shulei Zhang,Zul Kamal,Jing Su,Weien Yuan,Mingfeng Qiu
标识
DOI:10.1002/adhm.202002081
摘要
Abstract Immunotherapy will significantly impact the standard of care in cancer treatment. Recent advances in nanotechnology can improve the efficacy of cancer immunotherapy. However, concerns regarding efficiency of cancer nanomedicine, complex tumor microenvironment, patient heterogeneity, and systemic immunotoxicity drive interest in more novel approaches to be developed. For this purpose, biomimetic nanoparticles are developed to make innovative changes in the delivery and biodistribution of immunotherapeutics. Biomimetic nanoparticles have several advantages that can advance the clinical efficacy of cancer immunotherapy. Thus there is a greater push toward the utilization of biomimetic nanotechnology for developing effective cancer immunotherapeutics that demonstrate increased specificity and potency. The recent works and state‐of‐the‐art strategies for anti‐tumor immunotherapeutics are highlighted here, and particular emphasis has been given to the applications of cell‐derived biomimetic nanotechnology for cancer immunotherapy.
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