Overweight/obesity revisited as a predictive risk factor in primary IgA nephropathy

IgAN patients with an elevated BMI at diagnosis had a significantly worse presentation and worse final outcome. Overweight/obesity increased hypertension frequency, proteinuria level and some renal lesions all of which translate into a worse ARR for prediction of CKD-3+ or dialysis alone or dialysis/death, with no apparent direct effect of BMI per se.