Comparison of the anti-inflammation effects of Ermiao capsule composed of different breeds of Cortex Phellodendri

OBJECTIVE To investigate the anti-inflammation effects of Ermiao capsule composed of different breeds of Cortex Phellodendri.METHODS After swelling xylol induced in mouse ears or carrageenin induced swelling in rat hind paws,exudation of the pigment of rat derma caused by histamine.Ermiao capsule composed of different breeds of Cortex Phellodendri were administered,to observe the reaction of the animal model.RESULTS Ermiao capsule composed of Cortex Phellodendri amurensis had inhibitory effects on acute inflammation reaction.Ermiao capsule composed of Cortex Phellodendri chinensis had only inhibitory effects on acute inflammation reaction of mouse ears induced by xylol,but no effects on induced swelling in rat hind paws by carrageenin and exudation of the pigment of rat derma caused by histamine.CONCLUSION These results suggested that the effects of Ermiao capsule composed of Cortex Phellodendri amurensis are better than the effects of Ermiao capsule composed of Cortex Phellodendri chinensis in inhibition of acute inflammation reaction.