齐多夫定
纯红细胞再生障碍
医学
骨髓再生障碍
印度次大陆
贫血
骨髓
溶血
人类免疫缺陷病毒(HIV)
骨髓衰竭
再生障碍
骨髓抑制
免疫学
病毒学
内科学
化疗
病毒性疾病
生物
古代史
遗传学
干细胞
造血
历史
作者
Anuja Balakrishnan,Rohith Valsalan,Shubha Sheshadri,Vinay Pandit,M Vikas,Ravindra Agrawal
标识
DOI:10.4103/0253-7613.66845
摘要
Hematological abnormalities are frequent among human immunodeficiency virus (HIV)-infected patients and may be directly attributable to the virus or may be caused by opportunistic infections, neoplasms or drugs that cause bone marrow suppression or hemolysis. Pure red cell aplasia (PRCA) is an uncommon hematological disorder that causes anemia. We report a 37-year-old male with HIV infection who developed PRCA 6 weeks after commencing Zidovudine and recovered following cessation of the drug. This is the first case of Zidovudine-induced PRCA reported from the Indian subcontinent.
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