Synthesis of 1-H-1,2,3-triazole-1,4-naphthoquinones as potential antifungal agents

1,4-Naphthoquinone derivatives were found to possess remarkable biological activities, such as antimicrobial and anticancer. Chemical structures containing 1,4-naphthoquinone conjugated with 1,2,3-triazole are important building blocks for our research due to rapid preparation, as well as reported by us biological activities against T. cruzi and Leishmania parasites. In this work, we had interest in perform the synthesis of 1,2,3-triazole- 1,4-naphthoquinones using conventional protocols, and then study their antifungal activity.