Catalytic Asymmetric Transfer Hydrogenation of α-Ketoesters with Hantzsch Esters

C2-symmetric chiral copper(II)-bisoxazolines function as alcohol dehydrogenase mimics and catalyze highly enantioselective transfer hydrogenations of α-ketoesters with Hantzsch esters as a synthetic NADH analogue to give α-hydroxy esters in excellent enantioselectivities.