Noncadaveric human acellular dermal tissue is efficacious in treating lower eyelid retraction. BellaDerm produced long-term symptomatic relief and stable clinical correction of lower eyelid retraction secondary to multiple etiologies. These findings contradict the thinking that although acellular dermis is an adequate modality for correction of eyelid retraction, results may be compromised by graft resorption and recurrence of symptoms. Improved biological integrity from live donor harvesting or alternate processing techniques may contribute to the success of this particular acellular dermis.