When should I give corticosteroids to my patient withPneumocystispneumonia?

When should I give corticosteroids to my patient with Pneumocystis pneumonia? Q:Nonpregnant adult patients with human immunodefi ciency virus (HIV) and Pneumocystis jirovecii (formerly carinii) pneumonia (PJP) with hypoxemia should receive early adjunctive corticosteroids, along with anti-Pneumocystis therapy.Hypoxemia is defi ned as oxygen saturation less than 92% on room air, partial pressure of arterial oxygen (PaO 2 ) less than 70 mm Hg, or an alveolar-arterial oxygen (A-a O 2 ) gradient of 35 mm Hg or greater.Select patients without HIV infection who have hypoxemia may benefi t from early adjunctive corticosteroids, but there is no clear evidence that they should be used routinely.