Analytical Applications of Chemiluminescence in Flow-Injection Systems

Abstract Chemiluminescence (CL) detection, in combination with the flow injection (FI) technique, provides simple instrumentation approach characterized by rapid response time, low limits of detection, and reliable methodologies for examining a broad spectrum of analytes in diverse scientific domains of analytical chemistry. This review describes the chemiluminescent reactions involving CL reagents and certain oxidants, highlighting their recent analytical applications in the analysis of significant analytes present in environmental, pharmaceutical, biological, and food matrices using the FI technique. The literature review includes key analytical studies published from 2018 to mid-2024. The review concludes with insights and future perspectives in this area of research.