Advances in bimetallic materials and bimetallic oxide nanozymes: Synthesis, classification, catalytic mechanism and application in analytical chemistry

Bimetallic materials and bimetallic inorganics have the advantages of low preparation cost, stable performance, easy preservation and recycling, etc., which is the important materials of current nanozyme research. An in-depth understanding of the possible catalytic mechanisms from the aspect of material composition and structure will be helpful for the development of new and efficient nanozymes, which is of great significance for the rational regulation of nanozymes' activities. In this review, we systematically introduce the classification of bimetallic materials and bimetallic oxide nanozymes, their catalytic mechanisms, as well as the research progress in recent years in the fields of analytical chemistry, including colorimetric and electrochemical sensing, as well as biomedical analysis. We also present the current challenges faced by bimetal-containing nanozymes and future research priorities. This review is important for further understanding the nature of bimetallic nanozymes and for the development of novel nanomaterials with superior analytical functions.