Nanocomposite Assisted Green Synthesis of Polyvinylpyrrolidone-Silver Nanocomposite Using Pandanus atrocarpus Extract for Antiurolithiatic Activity

A simple technical which is based on in situ doping of polymers with metal nanocomposite such as Polyvinylpyrrolidone (PVP) with silver nanoparticles (Ag NPs) is elaborated. The fabricate polymer nanocomposites (PVP-Ag NCs) showed altered physical and chemical properties that can be useful in researches involving biological activities. The present study reports an eco-friendly and rapid method for the synthesis of PVP-AgNCs. The PVP-AgNCs is synthesized through a green synthetic method, where Pandanus atrocarpus extract was used to act as reducing and capping agent. It is observed that this method is very fast, suitable and the formed PVP-AgNCs took only 5 to 10 min of the reaction time preparation with less energy and non-toxic chemicals. PVP-Ag NCs was characterized by UV-Vis, FESEM, FTIR, and XRD for chemical, morphology and crystallinity behavior of PVP-AgNCs. The unique PVP-AgNCs UV-vis peak is recorded at 450 nm which confirming the synthesis of the nanocomposite. FESEM analysis showed the nanocomposite to be narrow in size ranging from 27 to 50 nm. It is believed that this is the first-ever report on investigating PVP-AgNCs for its antiurolithitaic activity through nucleation assay and dose-dependent. The PVP-Ag NCs powerful bioactivity demonstrated in this report could lead to clinical use as antiurolithiaitc agent.