New research progress in molecular mechanisms of colorectal liver metastasis

Colorectal cancer is one of the most common malignant tumor with high mortality rate. About a third of patients with colorectal cancer have either simultaneously or metachronous liver metastasis with poor prognosis. Therefore, the studies on the mechanisms of colorectal liver metastasis is significant. Recently, the research on the molecular mechanisms of colorectal liver metastasis is increasing, this paper summarizes some of them, and we hope providing new ideas for the diagnosis and treatment of colorectal cancer patients with liver metastasis. Key words: Colorectal neoplasms; Liver; Nnoplasms metastasis; Molecular mechanism; Review